Genome-Wide Association Study Identifies a Functional SIDT2 Variant Associated with HDL-C (High-Density Lipoprotein Cholesterol) Levels and Premature Coronary Artery Disease
León-Mimila, P., Villamil-Ramírez, H., Macías-Kauffer, L. R., Jacobo-Albavera, L., López-Contreras, B. E., Posadas-Sánchez, R., Posadas-Romero, C., Romero-Hidalgo, S., Morán-Ramos, S., Domínguez-Pérez, M., Olivares-Arevalo, M., López-Montoya, P., Nieto-Guerra, R., Acuña-Alonzo, V., Macín-Pérez, G., Barquera-Lozano, R., Del-Río-Navarro, B. E., González-González, I., Campos-Pérez, F., ? Canizales-Quinteros, S. (2021). Genome-Wide Association Study Identifies a Functional SIDT2 Variant Associated With HDL-C (High-Density Lipoprotein Cholesterol) Levels and Premature Coronary Artery Disease. Arteriosclerosis, Thrombosis, and Vascular Biology, 41(9), 2494?2508. https://doi.org/10.1161/atvbaha.120.315391
Low HDL-C (high-density lipoprotein cholesterol) is the most frequent dyslipidemia in Mexicans, but few studies have examined the underlying genetic basis. Our purpose was to identify genetic variants associated with HDL-C levels and cardiovascular risk in the Mexican population.